King of Pumps is the ultimate non-stim, nitric oxide boosting preworkout formula. It’s packed with 7ingredients, 4 of which are branded and all of which increase NO production via different mechanisms.Every ingredient used is at the clinical dose for maximum performance benefit. This article will detail each ingredient and its mechanism of action for increasing vasodilation, giving you a crazy pump during your workout.
L-citrulline: One of the most commonly used pump ingredients, citrulline increases vasodilation via raising plasma arginine levels. Arginine is extensively metabolized by arginase largely before it can bind with Nitric Oxide Synthase(eNOS). eNOS converts arginine into NO and increases blood flow and elevates cyclic guanosine monophosphate(cGMP).
Betaine: Betaine is the methyl derivative of the amino acid glycine and is found in various beets. It has many uses, including performance enhancing benefits from many different mechanisms: increased creatine production, increased GH production, stimulation of lipolysis(breaking down fat cells). However, it was included in this formula because of its ability to induce intracellular hyper-hydration.
GlycerPump™(min 65% glycerol): GlycerPump™ has become one of my favorite preworkout ingredients. It is a powdered form of glycerol, an osmolyte like betaine only much more powerful. Glycerol can hydrogen bond(attract) with water in very large quantities. Once it bonds with all these water molecules, it can drive them into your cells, blood and tissues, creating a massive cell swelling effect. This excess water can last up to 4hr before your body breaks down glycerol and you expel the excess water. One study showed that ingesting glycerol before exercise increased time to exhaustion by 28%. Glycerol is the perfect preworkout ingredient to get crazy pumps that last during your entire workout.
VasoDrive-AP™: VasoDrive-AP™ is a newer ingredient to hit the market and is a very unique one. It’s a vasodilator, but it works differently from any other pump ingredient out. VasoDrive-AP™ consists of 2 lactotripeptides: Valyl-prolyl-proline and Isoluecyl-prolyl-proline. These 2 molecules act as inhibitors of the enzyme angiotensin converting enzyme(ACE), an enzyme that causes vasoconstriction, increased blood pressure and heart function. There are 30 studies on these lactotripeptides and their effect on vasodilation, blood flow, and decreased blood pressure. One study showed that ACE can dramatically inhibit physical performance, presumably from lack of blood flow which carries oxygen and nutrients to your muscles. Data also suggests that VasoDrive-AP™ works better the longer you take it.
Endo-Pump™: Endo-Pump™ is an ingredient blend that I actually designed myself. It’s a blend of 3 different natural plant extracts in a specific ratio that includes polyphenols and nitrates to increase blood flow and blood vessel diameter. Each ingredient has plenty of human studies backing up that they do, in fact increase vasodilation all via different mechanisms of action. One ingredient works via the eNOS pathway, like arginine and citrulline. Another works on endothelial relaxation, which increases blood, oxygen and nutrient flow and blood vessel diameter. The last ingredient works as a phosphodiesterase 5(PDE5) inhibitor which increases the production of NO naturally by increasing cGMP which causes vasodilation. Prescription PDE5 inhibitors are commonly used for erectile dysfunction because of this mechanism. Together in the right ratio, Endo-Pump™ maximizes vasodilation and NO production to give you the ultimate pump in the gym.